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DENVER, CO - Brandon Moss hit two home runs on Tuesday and the Athletics downed the Rockies, 8-5, in the opener of a three-game interleague series.

Colorado scored four in the first inning, but Oakland responded with a six-run third, highlighted by a two-run blast from Moss, who was called up from the minors on Wednesday.

He added a solo shot in the fifth while Brandon Inge went 2-for-3 with a homer and two RBI, helping the A's halt a three-game skid.

Bartolo Colon (6-6) got the win, surrendering five runs on nine hits over five innings. Ryan Cook allowed runners to reach first and second in the ninth before recording three straight outs to earn his first career save.

Tyler Colvin and Todd Helton both hit solo home runs for the Rockies, who lost their sixth straight game and fell to 0-7 in interleague play on the season.

Jeremy Guthrie (3-5) was charged with seven runs on eight hits over five inning in the setback.